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Agree: top 10, didn't surpass Breaking Bad, Sopranos, The Shield (arguably best series close out ever), et alia; still great stuff from the showrunners. Felt it was missing an 'Ozymandias'-level episode near the end. Edit: Lalo has got to be in the running for most charismatic, entertaining...

Ridiculous statement. Do you see defenses abandoning all that space? You still have to cover: floaters and running bank shots from >10' feet out remain a staple of the game at high level varsity high school and up. Our own 2-3 zone is susceptible to foul line / midrange jumpers, and when we...

Yes, with one caveat: the low frequency of encountering zones injects some risk into predicting future performance against a zone using the entire body of data. The easy way to counter this: model using only the data against zones. I imagine you'll find enough data to model, and if not: run a...

Likewise, hope you're doing well. Please do PM me - I look forward to reading.

The fault lies not in the Bayesian analysis, but in the weighting of various parameters by whoever designed the model. My sense of Miyzawa's BPR is that it 'overweights' missed field goals and may discard too many possessions it deems as 'unhelpful' (e.g, when a game is out of hand). A fairly...

Bayesian analysis is a probabilistic approach to statistical analysis. In brief: one uses a distribution of historical data on the parameter of interest (say, assist %) and then applies this to estimate likelihood of future outcome for the same parameter (usually within a range). The trailing...

Bayesian analysis here points to Joe as the worst defender (lower number = worse defenive rating)

Eighty-five American dollars for Postmark? Irreconcilable. Get a Padron 1964 and a Col d'Orcia Brunello. Can even get a wedge of sottocenere with the $12-$15 left over.

I'll suggest that the synergistic effect of keeping two weaker players in the starting lineup - Bell and Williams - is the real issue. Concur that pinning it solely on Bell doesn't hold water, but putting it on the starting forward tandem... that I can get behind (and the analytics support the...

These are from Evan Miyakawa's Bayesian analytics page, correct? IIRC there was a stark delineation in both Efficiency Margin and +/- between the 'J4M' lineup and everyone else. Further the 30d delta in BPR shows Brown's trending up strongly as he's gotten more minutes, while Williams and Bell...

One of the Sisyphean tasks of medicine, cancer vaccines are particularly challenging: 1. We need to target specific proteins expressed by tumor cells (these vaccine targets are called antigens): cancer, by nature, is highly fluid - mutating constantly, evolving to adapt to your own body's...

Weighs in at an inexplicable 4200 pages... but your point remains directionally correct.

Pic of Bouknight passed out in driver's seat with bag of Doritos (and a Glock)

Forgive the pedantry, but... the final parts of a play, or episode(s) of a show, that (ideally) end the character arcs and resolve plot are by definition the denouement. Guess I'm glad it felt like one, although more of an erosion, or crumbling - they failed to maintain the intensity of the...

I'd posit Luka was hunting Lebron because he preferred single coverage over having to beat his defender plus Lebron as the help defender. Lebron's D was solid; he forced some tough shots (which Luka made) - but no one is coming to help when Lebron picks him up on a switch... so Luka's trading...

Was fortunate to find 1972 Pierre Ferrand when out to dinner last weekend. Fantastic.

Regal 12 or 18? Not critical that we differentiate, but there are some material deltas betwixt the two. You can sometimes filter out the individual components of the 18 under optimal conditions (e.g. Strathisla, Stratchlyde) so that tells me they're doing something right. Regardless: either...

Who cares?

Those box seats in the new $1.8B thumbprint stadium were too much to pass up during 'load management' windows. Besides, if he went to Dallas he'd no longer be able to wallow in the masochistic milieu of having 40+ dropped on him with high efficiency by the Slovenian Stallion. (I choose to...

Looks like a soiled thumbprint. Second round exit for Wayoff P and the Kawhiians; trades shortly thereafter.

Kawhi to Mavs? Just think, Day2: Luka and Kawhi together...

I believe he's a shooting guard... thus, the 2 who Knox.

That's what I heard as well: is it on twitter somewhere, from a good source? Great news if this all gets confirmed.

I've heard from sources I trust that - hard to believe - Giannis has no ligament tears. Likely bone bruise, and some capsule stress, but all ligaments intact. Not sure if this has been announced on social media yet, but if not I'm sure it will be in short order.

Just saw the Giannis injury; really unfortunate. My quick take: capsule damage, bone bruise (tibia impacting femur) appear to be the baseline here. Looked like 30 degrees hyperextension which is... a lot. I think I see some valgus here (joint bent inward) as well. Very likely that ACL and/or...

Correct: 7 seconds or fewer. Fairly straightforward rule: if dealing with discrete units, use fewer. Mass, or something not 'countable' (e.g., sugar) use less. You might also consider using 'higher' in place of more, given that seconds are quantifiable... but I'm on the cusp of providing...

The supps captured in your last para generally have a reasonable bolus of clinical data from fairly well-designed studies that demonstrates efficacy: no argument with most of them. Turmeric is particularly interesting (have been involved in several academic studies on similar chemical...

Knee replacement, almost certainly. I had a TKR done roughly 10 years ago due to severe trauma to the joint (sports injury; think Shawn Livingston). No pain / complications since. I lift weights regularly, and perform deadlifts weekly. I don't go nearly as heavy as I used to, but even 67% on...

Absolutely no clinical data, clear evidence, or well controlled studies in humans on NAD enhancers and joint condition, osteogenesis, or arthritis (data from the 1996 McAlindon, et al. study with 72 patients is sketchy, subjective, and was never reproduced). Even the 2020 Mehmel, et al. paper...

I concur entirely with HOFCeluck. Frankly, bone on bone = TKR. You'd be shocked at how rapid the recovery is, and most pts remain pain / complication free post procedure. You'll be glad you got through it, and likely regret it if you delay. There are any number of very capable orthos to...

Correct!

Midbrain is indeed part of the stem. ACE2 expression is likely high there as well, although I've seen discordant data from some groups (RNA). Difficult to ascribe headache to vaccine(s) with high confidence, but a reasonable thesis for sure. I'm not actively conducting research; rather, I...

Correct: high ACE2 expression in the pons and medulla oblongata. S1 spike protein can traverse the BBB. While I don't believe we've confirmed whether the virus in toto can get / has gotten through, the attendant cytokine storm is still sufficient to disrupt CNS function.

Both PCR and antigen tests show active infection. Antibody tests detect Abs your body has produced, which indicates past infection (although one could have a 'dormant' carrier status; we just don't know enough about SARS CoV2). The antigen test detects viral proteins, and deploys antibody...

How fortunate then that we took out VA in March 2016 to reach the Final Four. And of course we beat VA in conference play in February 2017, so they haven't beaten us every year in conference play. I'll take the E8 win and eschew their loss to a 16 seed. Recent history shows we have 2 F4s...

UMBC takes out VA by 20 It happens: teams get hot, and it's lights out. Does anyone think VA didn't deserve their 1 seed last year in light of the outcome on March 16, 2018? If so, I suspect (1) those espousing said view don't understand the NCAA tourney selection and seeding process, and (2)...

Meanwhile... in the ACC...

I'll second this. HD links have been accessible for most games this season. As always, 'X' out of popups, and be patient as you may have to close more than one. That said, de minimis effort to capture an HD stream irrespective of your geography and the indefensibly vacuous blackout policies.

Come on, mang... you forgot a critical step, without which the stream in question will prove recalcitrant: 1. Close pop ups 2. Enable flash 3. ??? 4. Profit!!

Key stat: attendance = 3,429. Traveled roughly 1,200 miles for an L... in an arena 33% full... nested in the lugubrious squalor of North Tampa. How very bleak a vista that conference offers.

Addendum, in the wake of your serial invectives: do let's discuss the virtue of the pharma industry, and the vast body of defensible, reproducible data that's the bedrock of pharmacology. I look forward to a productive dialogue where each of us comes armed with facts, data or - at minimum -...

You've made some rather sweeping claims, coupled with assertions that are objectively inaccurate regarding medical research universities in the US. I'll reply to this thread tomorrow, and look forward to hearing your thesis on the biochemistry that could underpin development of acute...

'The Shield' absolutely stuck it's landing: the final scene was flawless IMO. 'Breaking Bad' perhaps veered too far into deus ex machina gun territory, but the final scene was still very well done; in toto the final episode was masterful.

Was this... intentional? If so, my compliments.

This is the best news I've had in quite some time. Unfortunate Powers Boothe is no longer with us; he was exceptional as Tolliver.

Looks like a three foot long black tip reef shark... not really a mortal threat, but definitely capable of delivering a nasty nip that requires stitches or perhaps taking a finger. Small enough to clip through the bars, like a dachshund with fins. Interesting social interactions when this...

I think Alsacs' first team is spot on. I too have a hard time reconciling Russell's pedestrian offense (although many argue it would've been superfluous on those C's championship squads) with a first team nod. Chamberlain also doesn't quite get me there - just couldn't carry teams through (the...

Irresistible reference to 0.0 mandates the Wormer clip.

Announcers are spot on; it was absolutely a liver shot. Solar plexus is significantly higher and in the center of the torso; Lomachenko's left to the body caught Linares on his right side, near the bottom of the rib cage. Liver shots will drop you every time; worse than solar plexus shots for...