Hell yeah! While I certainly don't expect that to happen, it certainly could. Stranger things have happened. Hmmm... let me ponder that thought for a moment. I got it... like some team (not to mention any names), winning 25 straight games without a single loss to then follow that with losing 4 out of its next 5 (two of which are against 148+ RPI teams AT HOME).
Think about it, IF that were to happen, we are talking only four losses in the season and then winning the ACC tourney which would most likely mean two top notch wins (Duke, UNC, Virginia possibilities).