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[QUOTE="Townie72, post: 1700118, member: 780"]
The above analysis leads to what would have been the right strategy for Brackets in 2016.

In the First Round

Always pick the #1 Seeds *unless the #1 Seed happens to be Georgetown in which case picking against them and having it work out would be such a delicious experience)

Pick 75% of the 2, 3 and 4 seeds. One of them is going to lose.

When you get to beyond the 4 Seeds, seeding doesn't matter. You can't use it as a guide. So you have to:
1. Depend on superior basketball knowledge gained by actually watching hundreds of games during the season
2. Depend on your prejudices by picking teams you hope will win or hope will lose.
3. Depend upon systematic biases like always picking ACC schools or always picking Southern schools. 
4. Random selection, a variation my wife uses by picking school's she likes based upon whether she knows and likes people who went there or their mascots or their school colors. It's guaranteed that whoever wins the pools this year will have used one of these approaches since Townie's "ex post facto" process above was not available before the Tourney.
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