There's already a renewed and vigorous debate around 'will you let your son play football' in the aftermath of the Junior Seau suicide (which may or may not have anything to do with concussions, mind you).
That debate will soon progress to "will you let your kids watch football", and then become "will you watch football". I've long said that the only thing that can derail the NFL as being the most successful league in the world, and harm football as being the most lucrative media content to buy and sell, is continued catastrohpic injury and long term after-effects. I mean it's getting a bit ghoulish to be a fan.
I'm sure there are ways to mitigate the injuries and effects. Medical science is an amazing thing. I can't imagine playing without protection is the way to go. A 260 lb. guy who runs a 4.4 forty and has 0% body fat will literally kill someone someday if there is no protection. These ain't the 5'8", 160 lb. guys of 1925. Oh, and they killed people too.