Absolutely. There are definitely two sides to the coin and coaching philosophy makes a big difference.
Where I probably disagree with a lot of people, is that I don't place a premium on centering an offense around passing or the philosophy that everybody should touch the ball each possession. I'm okay with isolation.
As with anything, though, moderation is the key. You can't run Iso all the time like last season's team and you would be limiting yourself if you didn't take advantage of Iso mismatches because you want to pass the ball more. For instance, Fair needed to get the ball more on cuts, though he was still a solid isolation player; whereas, Melo needed the ball in isolation more because nobody could match up with him.
Boeheim adjusts to what he has on the court, from what I've seen. The Wes Johnson team shared the ball like it was nobody's business because, more or less, they had to and it fit the makeup of that team. I wouldn't agree that Jim B is overly dependant on isolation, if that's anybody's argument. He runs a pro style offense that tries to get the best player the ball. The players, and their willingness to pass, play a role in it, too. Ennis was an inexperienced PG that may not have understood the offense enough to get it running the way it should. I remember Flynn's teams sharing the ball more as he matured.