Sure it does.
5, 6, 7, 8 seeds are not protected in first round. Commitee places 5,6,7,8,9, 10, 11, 12 teams as close to home as possible while adhering to bracketing rules and keeping teams within one line of s-curve (conference teams cannot meet until E8, top 3 from each conference in different region). Bracketing rules make it difficult to place many 5-12 teams close to home.
If Cal had been a 13 seed it would not be in San Jose, because Syracuse is protected from such a matcup in first round. UNLV as a 5 seed is not.