Given the strengths of both of our defenses,
First off, I think what you said horribly overestimates the strength of our defense. Louisville's defense by the best objective measures we have is significantly better than our defense. We should not be relying on our defense to win games. Let's just keep in mind though going off of what you said that we are supremely confident in our defense.
I think a lot of folks, including myself, were expecting a low- scoring game.
People should never expect a low scoring game, and whenever I hear the announcers say that they talked with a coach and he said they were hoping for a low scoring game I know they're thinking like a meathead. Why would you ever coach to a low scoring game when you can coach to get the most production out of your offense?
Under this assumption, I think it was reasonable to play things conservatively in our first possession, not give away easy points on a TO, and play the field position game.
I cannot disagree more. First, let's just say you do want to battle in a low scoring game - you should play less conservatively, not more, because points in a low scoring game mean more. One of the things our offense does well is not turn the ball over - why are we that concerned about turning it over? Nassib doesn't throw picks. Ant has fumbled a few times, but overall, we don't turn it over much. Why does that scare us? This makes zero sense to me.
Now let's talk about the field position game - putting aside my general belief that playing for field position < just looking to get first downs and touchdowns, what exactly is the end game we're looking for on that drive? We go three and out, kick and give a short field, get the ball back because we trust our defense... but pinned back with a long field again. At some point if you want field position you have to earn it while you have the ball. Might as well have fought for that on our first possession, when we have L'Ville scouted and can throw something at them they haven't seen before. You know, because we're multiple after all. That's something our offense is supposed to be able to do.
Against WVA, I think the expectation was that we would be able to move the ball against the WVA defense; it was more a matter of stopping Geno Smith and the Neer offense. Completely different game management mindset.