IDK, every 2 vs 3 is for the sweet 16. Michigan State has 8 losses. I don't see anything out of the ordinary with them and to me not much if anything separates them from the other 3's; Florida, Marquette and New Mexico.
Is Duke really harder than the other #2s ; Georgetown, Miami or Ohio State? Miami not only won the ACC tourney, they won the regular season and split head to head with Duke. GTown won the Big East and beat LVille head to head and Ohio State won the Big 10.
St Louis? blah. Who's their biggest win? Butler, VCU ?
Louisville should cruise to the Elite 8 and at that point their opponent should be tough.