After games that are completed as of right now (6:45 EDT), Syracuse has flip-flopped with Harvard in the RPI, climbing to 10. I assume this is mostly due to the Towson win.
SU now has a SOS rank of 7. Vs. the top 5, we are 0-3 (MD, Cornell, UNC), 1-1 vs. 6-10 (ND, Duke), and 2-1 vs. 11-20 (UVa and Hop W's, #11 Harvard L).
Beating ND again would give us another 6-10 win, and winning on Sunday would be a top 10 win, depending on who we play. Whoever we play would probably be another 6-10 win - not sure Duke beating UNC would be enough to raise the Devils from 8 to 5 (or higher), and beating UNC would probably drop them from 5 (although beating Duke might keep them at 4 or 5).
Losing to ND, besides not being good for our chances, would probably give them a boost from 6, but that would leave us at 0-4 vs. the top 5. Obviously, many many variables.