Yes, that comment is from last week, and if there was anywhere in the city with the density to support it, it would be Armory Square. I mean, we are talking about one block on a street that is not a through street. It's supposed to be the centerpiece nightlife district in the city, and frankly it looks like crap. If the tiny city of Burlington can make Church Street pedestrian only for multiple blocks, then I think Syracuse could easily do the same with one block.
Main Street in Buffalo is in the process of reopening a number of blocks to vehicle traffic (it's about half-way done), although it wasn't the result of a failed pedestrian experiment. Main Street was closed to traffic when the Metro Rail line was built there. I wouldn't say the rail line made the street really all that more pedestrian-friendly, as I don't think that was part of the initial rail project goals.